… a great many innovations fall by the wayside, not so much because the initial idea was flawed but rather because some ancillary aspect prevented economical deployment on a large scale. Issues range from minor impurities or compositional variations .. market imbalances in byproduct streams … mismatches … with marketplace specifications…

From a business perspective, initial innovation is relatively easy and cheap; most of the risk resides in the expensive and lengthy scale-up and commercialization+ process. Therefore, choosing which innovations to take forward becomes a critical question.

The Biofuels Landscape Through the Lens of Industrial Chemistry, Willems